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Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems

Xuan Zheng, Sheng Lu, Liuhanzi Yang, Min Yan, Guangyi Xu, Xiaomeng Wu, Lixin Fu, Ye Wu

《环境科学与工程前沿（英文）》 2020年 第14卷 第2期 doi: 10.1007/s11783-019-1212-6

摘要： • Fuel consumption (FC) from LDPVs is measured using on-board diagnostic method (OBD). • The FC of the OBD is 7.1% lower than that of the carbon balance results. • The discrepancy between the approved FC and real-world FC is 13%±18%. • There is a strong relationship (R2=0.984) between the average speed and relative FC. An increasing discrepancy between real-world and type-approval fuel consumption for light-duty passenger vehicles (LDPVs) has been reported by several studies. Normally, real-world fuel consumption is measured primarily by a portable emission measurement system. The on-board diagnostic (OBD) approach, which is flexible and offers high-resolution data collection, is a promising fuel consumption monitoring method. Three LDPVs were tested with a laboratory dynamometer based on a type-approval cycle, the New European Driving Cycle (NEDC). Fuel consumption was measured by the OBD and constant-volume sampling system (CVS, a regulatory method) to verify the accuracy of the OBD values. The results of the OBD method and the regulatory carbon balance method exhibited a strong linear correlation (e.g., R2 = 0.906-0.977). Compared with the carbon balance results, the fuel consumption results using the OBD were 7.1%±4.3% lower on average. Furthermore, the real-world fuel consumption of six LDPVs was tested in Beijing using the OBD. The results showed that the normalized NEDC real-world fuel consumption of the tested vehicles was 13%±17% higher than the type-approval-based fuel consumption. Because the OBD values are lower than the actual fuel consumption, using a carbon balance method may result in a larger discrepancy between real-word and type-approval fuel consumption. By means of the operating mode binning and micro trip methods, a strong relationship (R2 = 0.984) was established between the average speed and relative fuel consumption. For congested roads (average vehicle speed less than 25 km/h), the fuel consumption of LDPVs is highly sensitive to changes in average speed.

关键词： Fuel consumption     Light-duty passenger vehicles     On-board diagnostic systems    

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基于时序优化长短期记忆和自适应阈值的高排放重型柴油车识别 Research Article

许镇义1,王仁军1,2,曹洋1,3,4,康宇1,3,4

《信息与电子工程前沿（英文）》 2023年 第24卷 第11期   页码 1633-1646 doi: 10.1631/FITEE.2300005

摘要： 在实际场景中，重型柴油车是城市氮氧化物的重要来源，其排放的氮氧化物（NOx）占车辆总排放量的80％以上，颗粒物（PM）占90％以上。检测和控制重型柴油车的排放对保护公众健康至关重要。目前，道路上的车辆必须每6个月或每年定期检测一次，在车辆检查站过滤出高排放的移动源。然而，由于年检间隔时间较长，很难及时有效地筛选出高排放车辆，而且固定的阈值不能适应车辆驾驶工况的动态变化。车载诊断设备（OBD）安装在车辆内部，可以连续跟踪和实时记录排放数据。本文提出一种时间优化长短期记忆（LSTM）和自适应动态阈值方法，使用OBD数据识别重型高排放车辆。首先，建立一个时间优化LSTM排放预测模型，以解决实际中大量OBD数据流造成的时间步注意力偏重问题。然后，利用灵活的阈值标准检测浓度预测误差序列，以区分异常排放情况，该阈值随驾驶条件变化自适应计算得到。最后，引入时间序列的相似性度量策略，以纠正一些假的异常结果。在3个真实OBD时间序列排放数据集上的实验表明，该方法得到优异的高排放源识别结果。

关键词： 高排放识别；时序优化；车载诊断设备（OBD）；动态阈值    

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螺旋结构冷却塔的塔板设计方法

黄锐

《中国工程科学》 2008年 第10卷 第11期   页码 43-46

摘要：

针对冷却塔中螺旋结构类型的气液交换塔，提出其内部螺旋塔板形状的设计方法，包括塔壁上外螺旋线和塔中心轴管上内螺旋线的位置确定，以及两线之间螺旋曲面板在平面上的拓扑尺寸。通过塔的几何参数确定螺旋曲面板设计的关键参数，可实现扭曲状塔板与塔壁及内轴的准确配合。

关键词： 冷却塔     塔板设计     螺旋曲面     拓扑    

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Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

《医学前沿（英文）》 2022年 第16卷 第5期   页码 723-735 doi: 10.1007/s11684-021-0905-y

摘要： Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. At present, no definite ALS biomarkers are available. In this study, exosomes from the plasma of patients with ALS and healthy controls were extracted, and differentially expressed exosomal proteins were compared. Among them, the expression of exosomal coronin-1a (CORO1A) was 5.3-fold higher than that in the controls. CORO1A increased with disease progression at a certain proportion in the plasma of patients with ALS and in the spinal cord of ALS mice. CORO1A was also overexpressed in NSC-34 motor neuron-like cells, and apoptosis, oxidative stress, and autophagic protein expression were evaluated. CORO1A overexpression resulted in increased apoptosis and oxidative stress, overactivated autophagy, and hindered the formation of autolysosomes. Moreover, CORO1A activated Ca2+-dependent phosphatase calcineurin, thereby blocking the fusion of autophagosomes and lysosomes. The inhibition of calcineurin activation by cyclosporin A reversed the damaged autolysosomes. In conclusion, the role of CORO1A in ALS pathogenesis was discovered, potentially affecting the disease onset and progression by blocking autophagic flux. Therefore, CORO1A might be a potential biomarker and therapeutic target for ALS.

关键词： amyotrophic lateral sclerosis     coronin-1a     autophagy     pathogenesis    

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Obesity in China: its characteristics, diagnostic criteria, and implications

null

《医学前沿（英文）》 2015年 第9卷 第2期   页码 129-133 doi: 10.1007/s11684-015-0387-x

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Meta-analysis of the diagnostic efficiency of frequency-doubling technology for primary glaucoma

LIU Ting, HE Xiangge

《医学前沿（英文）》 2007年 第1卷 第1期   页码 109-114 doi: 10.1007/s11684-007-0021-7

摘要： The overall diagnostic capabilities and utility of frequency-doubling technology (FDT) in patients with primary glaucoma, which was diagnosed by standard automated perimetry (SAP) and/or optic disc appearance as the gold standard, were assessed. A comprehensive electric retrieval in MEDLINE, EMBASE, Cochrane Library, BIOSIS, Previews, HMIC, IPA, OVID, CNKI, CBMdisc, VIP information, CMCC, CCPD, SSreader, 21dmedia and manual retrieval in related textbooks, journals, congress articles and their references at home and abroad were performed to identify relevant articles in English or Chinese. The corresponding references were retrieved by means of electric retrieval and manual retrieval from different databases or materials. Criteria for inclusion or exclusion were established according to validity criteria for diagnostic studies published by the Cochrane Methods Group on Screening and Diagnostic Tests. The quality of the included articles was then assessed and characteristics were extracted. Statistical analysis was performed with Meta Test version 0.6 software to test the heterogeneity of the included articles. The appropriate effects model was selected to calculate pooled weighted sensitivity and specificity. Summary receiver operating characteristic (SROC) curve was drawn and the area under the curve (AUC) was calculated. Finally, sensitivity analysis was performed. Twenty-one studies out of 206 retrieved articles were included, with a total of 3172 patients. The reported sensitivity of FDT ranged from 0.51 to 1.00, and specificity from 0.58 to 1.00. The pooled weighted sensitivity and specificity of FDT with 95% confidence intervals (95% CI) after correction for standard error were 0.86 (0.80 0.90) and 0.87 (0.81 0.91), respectively. The AUC of SROC was 93.01%. Sensitivity analysis demonstrated no disproportionate influences of individual studies. The included articles are of good quality and FDT can be a highly efficient diagnostic test for primary glaucoma based on Meta-analysis.

关键词： inclusion     sensitivity analysis     correction     specificity     appropriate    

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面向机床的可重构监测诊断系统开发与应用

景敏卿,李猛,刘恒

《中国工程科学》 2013年 第15卷 第1期   页码 34-38

摘要：

提出了一种基于“系统引擎+功能组件”的监测诊断系统平台架构，并针对机床4大功能部件模块，设计了3类（振动、功率和声发射）嵌入式监测单元，以强化底层监测信息获取的实时性和灵活性。笔者还开发了一系列机床常规监测诊断组件，并针对具有特殊监测诊断需求的数控机床功能部件，开发了相应的特殊功能组件，通过对功能组件的封装和加载实现具有特定需求的机床监测诊断系统，并在秦川磨床厂和大连机床厂进行实际应用。

关键词： 机床监测诊断系统     可重构     系统引擎     功能组件    

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An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

null

《医学前沿（英文）》 2013年 第7卷 第4期   页码 506-509 doi: 10.1007/s11684-013-0294-y

摘要：

This study aimed to investigate patient dose in diagnostic screen-film radiographic examinations in the city of Lhasa, China. Seven out of the twenty-six hospitals registered with the Lhasa Health Bureau were included in the investigation. The entrance surface air Kerma (ESAK) of seven conventional screen-film radiology X-ray equipment in these hospitals was measured with a QA dosimeter in September 2012. The X-ray examinations were divided into three categories: PA (posterior-anterior) chest, upper/lower limb, and AP (anterior-posterior) lumbar spine. For each category, ESAKs were calculated and analyzed. The mean ESAK was 0.6 mGy for PA chest, 0.3 mGy for upper/lower limb, and 1.8 mGy for AP lumbar spine. In addition, the mean ESAK value recorded for PA chest X-ray examinations exceeded the corresponding value recommended by the International Atomic Energy Agency (0.4 mGy).

关键词： radiation dosage     radiology     radiation protection     radiography/statistics & numerical data    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

《医学前沿（英文）》 2012年 第6卷 第3期   页码 243-247 doi: 10.1007/s11684-012-0201-y

摘要： Diabetes has become a major public health problem in China nowadays. There are almost 97 million diabetic patients nationwide. Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes. Although it has been reported for about 20 years, the diagnostic criteria of this disease remain controversial. The discussion mainly focused on serum autoantibodies, period of insulin need and age of diagnosis. Besides, β cell function, metabolic parameters, genetic factors and cell immunity may also contribute to the formulation of the criteria. Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

关键词： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic alongside diagnostic

《医学前沿（英文）》 2022年 第16卷 第6期   页码 827-858 doi: 10.1007/s11684-022-0948-8

摘要： Infertility is experienced by 8%–12% of adults in their reproductive period globally and has become a prevalent concern. Besides routine therapeutic methods, stem cells are rapidly being examined as viable alternative therapies in regenerative medicine and translational investigation. Remarkable progress has been made in understanding the biology and purpose of stem cells. The affected pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) are further studied for their possible use in reproductive medicine, particularly for infertility induced by premature ovarian insufficiency and azoospermia. Accordingly, this study discusses current developments in the use of some kinds of MSCs such as adipose-derived stem cells, bone marrow stromal cells, umbilical cord MSCs, and menstrual blood MSCs. These methods have been used to manage ovarian and uterine disorders, and each technique presents a novel method for the therapy of infertility.

关键词： infertility     stem cell therapy     mesenchymal stem cells     pluripotent stem cells    

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Intelligent fault diagnostic system based on RBR for the gearbox of rolling mills

Lixin GAO, Lijuan WU, Yan WANG, Houpei WEI, Hui YE

《机械工程前沿（英文）》 2010年 第5卷 第4期   页码 483-490 doi: 10.1007/s11465-010-0118-6

摘要： This paper presents an intelligent system that is necessary for diagnostic accuracy and efficiency in the iron and steel industry. A rule-based reseaning (RBR) intelligent diagnostic system has been developed based on many successful diagnostic applications. It can solve the difficulty in knowledge acquisition and has more precision. Its application results prove that the usability of the system is good and it will increasingly attain perfection.

关键词： rule-based reasoning     fault diagnosis     intelligent system     gear box    

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iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnostic

null

《医学前沿（英文）》 2016年 第10卷 第3期   页码 278-285 doi: 10.1007/s11684-016-0453-z

摘要：

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. We aimed to find novel molecules as potential biomarkers for the early diagnosis of CRC. A serum-free conditioned medium was successfully collected from three pairs of CRC tissue and adjacent normal tissue. iTRAQ-based quantitative proteomic analysis was applied to compare the differences in secretome between primary CRC mucosa and adjacent normal mucosa. A total of 145 kinds of proteins were identified. Of these proteins, 29 were significantly different between CRC and normal tissue. Tropomyosin 2 β (TPM2) exhibited the most significant differences; as such, this protein was selected for further validation. Quantitative real-time PCR indicated that the mRNA expression of TPM2 significantly decreased in the CRC tissue compared with the paired adjacent normal tissue. Immunohistochemical analysis also confirmed that TPM2 was barely detected at protein levels in the CRC tissue. In summary, this study revealed potential molecules for future biomarker applications and provided an efficient approach for the differential analysis of cancer-associated secretome. TPM2 may be valuable for the early diagnosis of CRC.

关键词： iTRAQ     secretome     colorectal cancer     TPM2    

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Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

《医学前沿（英文）》 2020年 第14卷 第1期   页码 91-100 doi: 10.1007/s11684-019-0696-6

摘要： Pancreatic ductal adenocarcinoma (PDAC) is the ninth most common human malignancy and the sixth leading cause of cancer-related death in China. AcK27-HOXB9 is a newly identified HOXB9 post-transcriptional modification that can predict the outcome in lung adenocarcinoma and colon cancer well. However, the role of AcK27-HOXB9 in PDAC is unclear. The present study aims to investigate the differential diagnostic role of patients with AcK27-HOXB9 PDAC. Tissue microarrays consisting of 162 pancreatic tumor tissue samples from patients with PDAC and paired normal subjects were used to examine HOXB9 and AcK27-HOXB9 levels and localizations by immunohistochemical analysis and Western blot assay, respectively. HOXB9 was upregulated ( <0.0001), and AcK27-HOXB9 ( =0.0023) was downregulated in patients with PDAC. HOXB9 promoted ( =0.0115), while AcK27-HOXB9 ( =0.0279) inhibited PDAC progression. AcK27-HOXB9 predicted favorable outcome in patients with PDAC ( =0.0412). AcK27-HOXB9 also suppressed PDAC cell migration in a cell migration assay. The results of this study showed that HOXB9 promoted and AcK27-HOXB9 suppressed PDAC progression. The determination of ratio between HOXB9 and AcK27-HOXB9 exhibited potential diagnostic value in patients with PDAC.

关键词： HOXB9     AcK27-HOXB9     PDAC    

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增材制造专题引言

增材制造专题编委会

《工程（英文）》 2017年 第3卷 第5期 doi: 10.1016/J.ENG.2017.05.027

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大型风力机组远程智能监测与诊断系统的研究与开发

杨文广,蒋东翔

《中国工程科学》 2015年 第17卷 第3期   页码 24-29

摘要：

该文研究了大型风力机组的远程智能监测与诊断系统的关键技术问题，介绍了系统的开发情况。整个系统采用分布式架构，由数据采集与处理、实时数据存储、智能监测与诊断和人机交互4个子系统组成。智能监测与诊断子系统采用了知识库/推理机架构，推理机是一个自主开发的基于模糊Rete算法的模糊专家系统，知识库中存储了来源于风力机故障实验研究的常见振动故障的诊断知识。通过故障仿真，验证了整套系统的有效性。

关键词： 风力机；故障诊断系统；模糊专家系统    

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标题 作者 时间 类型 操作

Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems

Xuan Zheng, Sheng Lu, Liuhanzi Yang, Min Yan, Guangyi Xu, Xiaomeng Wu, Lixin Fu, Ye Wu

期刊论文

基于时序优化长短期记忆和自适应阈值的高排放重型柴油车识别

许镇义1,王仁军1,2,曹洋1,3,4,康宇1,3,4

期刊论文

螺旋结构冷却塔的塔板设计方法

黄锐

期刊论文

Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

期刊论文

Obesity in China: its characteristics, diagnostic criteria, and implications

null

期刊论文

Meta-analysis of the diagnostic efficiency of frequency-doubling technology for primary glaucoma

LIU Ting, HE Xiangge

期刊论文

面向机床的可重构监测诊断系统开发与应用

景敏卿,李猛,刘恒

期刊论文

An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

null

期刊论文

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

期刊论文

treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic alongside diagnostic

期刊论文

Intelligent fault diagnostic system based on RBR for the gearbox of rolling mills

Lixin GAO, Lijuan WU, Yan WANG, Houpei WEI, Hui YE

期刊论文

iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnostic

null

期刊论文

Acetylated HOXB9 at lysine 27 is of differential diagnostic value in patients with pancreatic ductal

Xiaoran Sun, Jiagui Song, Jing Zhang, Jun Zhan, Weigang Fang, Hongquan Zhang

期刊论文

增材制造专题引言

增材制造专题编委会

期刊论文

大型风力机组远程智能监测与诊断系统的研究与开发

杨文广,蒋东翔

期刊论文